Tuesday, June 13, 2017

History of H5N1

On May 5, 1997, H5N1 human avian influenza was firstly found in Hong Kong of China in a 3-year old child, who died from Reye syndrome and multiple organ failure 1 day after onset of the diseases. The diagnostic laboratory isolated an influenza A virus but could not identify its H subtype with any reagent available to them.

In November, as second Hong Kong boy – this time two year old fell ill. Again the cause was the H5N1. The boy did not die. In mid November, however, a third case emerged when 37 year old man wad diagnosed a s having H5N1 related symptoms.
 On May 9, the US CDC and Rotterdam state influenza center of WHO laboratory isolated the H5N1 AIV strain from the bronchial secretions of this 3-year-old boy which was named “A/HongKong/157/97.”

It caused considerable concern about a potential pandemic. Since then, several influenza A viruses of avian origin that cause human disease have been isolated.

Scientists and public health authorities are watching H5N1 very closely. Since 2003, some 6 human cases have been reported in 15 countries.

In September 2005, the UN warned that an outbreak of avian influenza could kill between 5 to 150 million people, suddenly all the world’s attention was focused on this. In 2013, GlaxoSmithKline announced the first FDA-approved vaccine for a strain of H5N1.
History of H5N1
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